Publikationen

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2014

Ludwig B, Barthel A, Reichel A, Block NL, Ludwig S, Schally AV, Bornstein SR.Modulation of the pancreatic islet-stress axis as a novel potential therapeutic target in diabetes mellitus. EVitam Horm. 2014 (PubMed)

Hamann C, Picke AK, Campbell GM, Balyura M, Rauner M, Bernhardt R, Huber G, Morlock MM, Günther KP, Bornstein SR, Glüer CC, Ludwig B, Hofbauer LC.Effects of parathyroid hormone on bone mass, bone strength, and bone regeneration in male rats with type 2 diabetes mellitus.
Endocrinology. 2014 Jan 27. [Epub ahead of print] (PubMed)

2013

Ludwig B, Reichel A, Steffen A, Zimerman B, Schally AV, Block NL, Colton CK, Ludwig S, Kersting S, Bonifacio E, Solimena M, Gendler Z, Rotem A, Barkai U, Bornstein SR.
Transplantation of human islets without immunosuppression.
Proc Natl Acad Sci U S A. 2013 Oct 28. [Epub ahead of print] (PubMed)

Phieler J, Chung KJ, Chatzigeorgiou A, Klotzsche-von Ameln A, Garcia-Martin R, Sprott D, Moisidou M, Tzanavari T, Ludwig B, Baraban E, Ehrhart-Bornstein M, Bornstein SR, Mziaut H, Solimena M, Karalis KP, Economopoulou M, Lambris JD, Chavakis T.
The complement anaphylatoxin C5a receptor contributes to obese adipose tissue inflammation and insulin resistance.
J Immunol. 2013 Sep 16. [Epub ahead of print] (PubMed)

Neufeld T, Ludwig B, Barkai U, Weir GC, Colton CK, Evron Y, Balyura M, Yavriyants K, Zimermann B, Azarov D, Maimon S, Shabtay N, Rozenshtein T, Lorber D, Steffen A, Willenz U, Bloch K, Vardi P, Taube R, de Vos P, Lewis EC, Bornstein SR, Rotem A
The efficacy of an immunoisolating membrane system for islet xenotransplantation in minipigs.
PLoS One. 2013 Aug 1(PubMed)

Reichel A, Rietzsch H, Ludwig B, Röthig K, Moritz A, Bornstein SR.
Self-adjustment of insulin dose using graphically depicted self-monitoring of blood glucose measurements in patients with type 1 diabetes mellitus.
J Diabetes Sci Technol. 2013;7(1):156-162. (PubMed)

Vimaleswaran KS. et al.
Causal relationship between obesity and vitamin D status: bi-directional Mendelian randomization analysis of multiple cohorts.
PLoS Med. 2013 Feb 5. [Epub ahead of print] (PubMed)

Schubert U, Schmid J, Lehmann S, Zhang XY, Morawietz H, Block NL, Kanczkowski W, Schally AV, Bornstein SR, Ludwig B.
Transplantation of pancreatic islets to adrenal gland is promoted by agonists of growth-hormone-releasing hormone.
Proc Natl Acad Sci U S A. 2013 Jan 23. [Epub ahead of print] (PubMed)

2012

Barkai U, Weir GC, Colton CK, Ludwig B, Bornstein SR, Brendel MD, Neufeld T, Bremer C, Leon A, Evron Y, Yavriyants K, Azarov D, Zimermann B, Maimon S, Shabtay N, Balyura M, Rozenshtein T, Vardi P, Bloch K, de Vos P, Rotem A.
Enhanced Oxygen Supply Improves Islet Viability in a New Bioartificial Pancreas.
Cell Transplant. 2012 Oct 3. [Epub ahead of print]

Ludwig B. et al.
Improvement of islet function in a bioartificial pancreas by enhanced oxygen supply and growth hormone releasing hormone agonist.
Proc Natl Acad Sci U S A. 2012;109(13):5022-7.

Uhlmann D, Weber T, Ludwig S, Ludwig B, Bartels M, Hauss J, Jonas S, Witzigmann H.
Long-term outcome of conversion to sirolimus monotherapy after liver transplant.
Exp Clin Transplant. 2012;10(1):30-8.

2011

Chambers JC. et al.
Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma.
Nat Genet. 2011;43(11):1131-8.

International Consortium for Blood Pressure Genome-Wide Association Studies et al.
Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk.
Nature. 2011;478(7367):103-9.

Strawbridge RJ. et al.
Genome-wide association identifies nine common variants associated with fasting proinsulin levels and provides new insights into the pathophysiology of type 2 diabetes.
Diabetes. 2011;60(10):2624-34.

Schmid J, Ludwig B, Schally AV, Steffen A, Ziegler CG, Block NL, Koutmani Y, Brendel MD, Karalis KP, Simeonovic CJ, Licinio J, Ehrhart-Bornstein M, Bornstein SR.
Modulation of pancreatic islets-stress axis by hypothalamic releasing hormones and 11beta-hydroxysteroid dehydrogenase.
Proc Natl Acad Sci U S A. 2011;108(33):13722-7.

Steffen A, Ludwig B, Krautz C, Bornstein S, Solimena M.
Functional assessment of automatically sorted pancreatic islets using large particle flow cytometry.
Islets. 2011;3(5):267-70.

Speliotes EK. et al.
Genome-wide association analysis identifies variants associated with nonalcoholic fatty liver disease that have distinct effects on metabolic traits.
PLoS Genet. 2011;7(3):e1001324.

Fox ER. et al.
Association of genetic variation with systolic and diastolic blood pressure among African Americans: the Candidate Gene Association Resource study.
Hum Mol Genet. 2011;20(11):2273-84.

Ziegler CG, Langbein H, Krug AW, Ludwig B, Eisenhofer G, Ehrhart-Bornstein M, Bornstein SR.
Direct effect of dehydroepiandrosterone sulfate (DHEAS) on PC-12 cell differentiation processes.
Mol Cell Endocrinol. 2011;336(1-2):149-55.

2010

Speliotes EK. et al.
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index.
Nat Genet. 2010;42(11):937-48.

Heid IM. et al.
Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution.
Nat Genet. 2010;42(11):949-60. Erratum in: Nat Genet. 2011;43(11):1164.

Ludwig B, Ludwig S, Steffen A, Saeger HD, Bornstein SR.
Islet versus pancreas transplantation in type 1 diabetes: competitive or complementary?
Curr Diab Rep. 2010;10(6):506-11.

Ludwig B, Ziegler CG, Schally AV, Richter C, Steffen A, Jabs N, Funk RH, Brendel MD, Block NL, Ehrhart-Bornstein M, Bornstein SR.
Agonist of growth hormone-releasing hormone as a potential effector for survival and proliferation of pancreatic islets.
Proc Natl Acad Sci U S A. 2010;107(28):12623-8.

2009

Yesil P, Michel M, Chwalek K, Pedack S, Jany C, Ludwig B, Bornstein SR, Lammert E.
A new collagenase blend increases the number of islets isolated from mouse pancreas.
Islets. 2009;1(3):185-90.

2008

Hanson MS, Steffen A, Danobeitia JS, Ludwig B, Fernandez LA.
Flow cytometric quantification of glucose-stimulated beta-cell metabolic flux can reveal impaired islet functional potency.
Cell Transplant. 2008; 17(12):1337-47.